It is safe, personally I only put one 3PAR port in the alias but I have done this for other arrays.
The safe/unsafe bit comes from when you do the zoning.
Again personally for 3PAR I use single Initiator/Single target zoning.
Some of the HPE guides state to use single Initiator/Multi tartget zoning (I do this for Nexsan and Nimble arrays but only ever a single array in the zone).
The main thing to avoid is multi initiators, never have more then one server port in a zone.
The HPE recommendation I think comes from the XP arrays, where they only work if the server port exists in a single zone, so if the server needs access to 3PAR, XP, MSA and Nimble arrays you need to put all the array ports into one zone with the single server port. If you don't have XP arrays (or some other array that needs this arrangement) then personally I'd avoid that.
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